A Lynn man was injured in the fatal crash on the A10 at Brandon Creek this morning (Wednesday, February 18).
Two men were killed after the black Austin Mini they were travelling in was involved with a collision with a green Volkswagen Passat.
The driver of the Passat, a 27-year-old man from Lynn, suffered slight injuries.
Cambridgeshire police would like to speak to anyone who saw the collision, that happened at about 6.45am, or either the Passat or Mini just prior.
A lorry and another car were also involved in the collision but were not badly damaged and no-one else was injured.
The road was closed to allow investigations and recovery to take place but it is expected to reopen soon.
Anyone with information should contact Sergeant Steve Watson on 101.